CBT-001 demonstrates good ocular and systemic safety, quick onset, and highly effective during and post-dosing.
Baseline demographic characteristics were similar between patients receiving CBT-001 (n=25) and vehicle (n=23). After four (4) weeks of dosing, mean vascularity scores were significantly decreased in patients receiving CBT-001 (-0.8) compared to vehicle (0.0) (p<0.001). Vascularity remained significantly decreased at weeks 8 (p=0.008) and 16 (p<0.001), but not at week 24. The CBT-001 group showed significantly greater mean reductions in lesion length at week 2 (p=0.005), week 4 (p=0.007) and week 8 (p=0.0145).